Amino Acids and Serum Proteins (Advances in Chemistry 044) by Jacob A. Stekol

By Jacob A. Stekol

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49, 25 (1961). , Biochemistry 1, 694 (1962). , Abstracts, 134th Meeting ACS, p. 60C, 1958. , Federation Proc. 14, 134 (1955). (37) Schultz, J . , Arch. Biochem. Biophys. 57, 174 (1955). , 50, 124 (1954). (39) Smith, E. , Brown, D. M . , McFadden, M . , Jager, Β. , J. Biol. Chem. 216, 601 (1955). (40) Smith, E . , 207, 501 (1954). , Biochem. J. 61, 629 (1955). (42) Sober, Η. , Wyckoff, M. , Peterson, Ε. , J. Am. Chem. Soc. 78, 756 (1956). (43) Sorensen, S. P. L . , Compt. Rend. Trav. Lab. Carlsberg 18 (5), 1 (1930).

It i s p o s s i b l e that a peptide of c o m p o s i t i o n s e r , t h r , g l u , g l y , v a l , i l e u , leu could be p r e s e n t i n e a c h p r o t e i n . B a s i c a m i n o a c i d s a r e absent. The r e m a r k a b l e s i m i l a r i t y i n the m o l a r r a t i o s of the a m i n o a c i d s offers encouragement to the p r o p o s i t i o n that c o m m o n peptides w i l l be found i n the e l e c t r o p h o r e t i c components of the s e r u m p r o t e i n s . The peptide of spot 7 p r o b a b l y d i f f e r s f r o m spot 8 i n l e u c i n e content, w h i c h would account f o r the h i g h e r R f of spot 8.

Y. Acad. Sci. 94, 31 (1961). (4) Block R. , J. Biol. Chem. 103, 261 (1933). , 105, 455, 461 (1934). (6) Block, R. , Durrum, E . , "Paper Chromatography and Paper Electrophoresis," Academic Press, New York, 1958. , in Schmidt, C. L. , "Chemistry of Amino Acids and Proteins," p. , 1938. (8) Block, R. , Yale J. Biol Med. 7, 235 (1935). (9) Brand, E . , Ann. Ν. Y. Acad. Sci. 47, 187 (1946). (10) Brand, E . , Edsall, J. , Ann. Rev. Biol. Chem. 16, 233 (1947). , Biochem. J. 88, 2Ρ (1963). (12) Crampton, C.

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